Abstract The main advantages of microneedles are precise drug delivery through human skin. minimal tissue damage and painlessness. We conducted structural analysis and skin puncture studies of hollow microneedles using ANSYS for three materials: Hafnium Dioxide (HfO2). Polyglycolic acid (PGA) and Polylactic acid (PLA). https://www.roneverhart.com/ESP-LTD-SD-2-Sammy-Duet-Signature-Model-Electric-Guitar-Black-p20045/