Abstract Background Reduced representation bisulfite sequencing (RRBS) was developed to measure DNA methylation of high-CG regions at single base-pair resolution. and has been widely used because of its minimal DNA requirements and cost efficacy; however. the CpG coverage of genomic regions is restricted and important regions with low-CG will be ignored in DNA methylation profiling. T... https://www.roneverhart.com/1915-Old-Taylor-Bourbon-Bottled-1933-Prohibition-Bottling-Quart-low-fill/
Double restriction-enzyme digestion improves the coverage and accuracy of genome-wide CpG methylation profiling by reduced representation bisulfite sequencing
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